Ferguson revealed the bad weather this week has meant United have done less arduous training sessions than he had hoped, which has cost Rooney the vital edge he needed to start against the Hammers.
The United manager intends to speak with Capello to give the Italian the latest update on Rooney's fitness, but will leave it to the England coach to make the final decision.
Capello is due to name his squad on Saturday evening and Rooney would almost certainly be part of it if the England coach feels he can make a worthwhile contribution.
Indeed, Rooney might actually benefit from a 20-minute substitute appearance, although Ferguson has made it clear that is a decision Capello must take for himself.
"I have not spoken to Fabio but I hope to do so in order to explain the situation," said Ferguson.
"He can then decide after dialogue with the physios whether it is worth taking Wayne to Seville.
"I have no strong issue with that. It is a question of whether he would play or be a substitute, which is the same position as I am in.
"It is up to Fabio. I really have no strong objection to that."
Ferguson also confirmed Gary Neville will miss the West Ham trip with a virus that forced him to come off against Everton last Saturday.
His automatic replacement, Wes Brown, does have a bruised foot, but is expected to play.