Author Mike Enslin's (Cusack) search for the supernatural has come up empty and as a result he's resorted to writing books such as top 10 haunted hotels in which he falsely claims to have had supernatural experiences. Despite the writing of these books his personal belief in the supernatural is far more sceptical. His latest research subject for these books is a hotel room in New York City with an ominous past. In his determination to prove the room's not haunted, Enslin may stumble into a real-life horror story.
source: http://en.wikipedia.org/wiki/1408_(film)
From the trailer looks like an interesting movie